Principles of pharmacogenetics and pharmacogenomics - Altman, Russ.; Flockhart, David A.; Goldstein, David B. (Cambridge ; New York : Cambridge University Press, 2012)
Part 1. Critical Concepts: Introduction to population diversity and genetic testing -- Genotyping technologies - - Pharmacokinetics: absorption, distribution, metabolism, excretion -- Overview: adverse drug reactions -- PharmGKB,a centralized resource for pharmacogenomic knowledge and discovery -- DrugBank -- Ethical considerations for pharmacogenomics: privacy and confidentiality -- Informedconsent in pharmacogenomic research and treatment -- Legal trends driving the clinical translation of pharmacogenomics -- Part 2. Therapeutic Areas: Oncologic drugs -- Pharmacogenetics and pharmacogenomics -- Statin-induced muscle toxicity -- Genomics of the drug-induced long-QT syndrome -- Pharmacogenetics of diabetes -- Pharmacogenetics - therapeutic area - respiratory -- Pharmacogenomics associated with therapy for acid-related disorders -- Pharmacogenetics of rheumatology: focus on rheumatoid arthritis -- Pharmacogenetics of obstetric therapeutics -- Pharmacogenomics of psychiatric drugs -- Pain and anesthesia -- HIV and antiretroviral therapy -- Application of pharmacogenetics and pharmacogenomics in pediatrics: what makes children different? -- Fetal and neonatal pharmacogenomics
Includes bibliographical references
Keywords: Pharmacogenetics; Pharmacological Phenomena -- genetics