APC proteins - McCartney, Brooke M. (Brooke Marie) (New York, N.Y. : Springer Science+Business Media ; Austin, Tex. : Landes Bioscience, 2009)
APC and [beta]-catenin degradation -- Nuclear APC -- APC in cell migration -- The APC-EB1 interaction -- The role of APC in mitosis and in chromosome instability -- Role of APC and its binding partners in regulating microtubules in mitosis -- The adenomatous polyposis coli tumor -- Suppressor and Wnt signaling in the regulation of apoptosis -- APC and its modifiers in colon cancer -- Tissue-specific tumour suppression by APC -- Extra-colonic manifestations of familial adenomatous polyposis coli.
Includes bibliographical references and index.
Keywords: Colon (Anatomy) -- Cancer; Tumor suppressor proteins; Adenomatous Polyposis Coli Protein